Preliminary Program



Monday, November 25

12:00               Registration opens 

13:30 - 13:50  Welcome by organizers

13:50 - 14:40 Keynote lecture by Melanie Stefan on Rule-based modelling of protein regulation in the synapse

14:40 - 15:30 Keynote Lecture by Birgit Schöberl on The Role of Quantitative Systems Pharmacology in Translational Medicine

Coffee break

16:15 - 17:05 Keynote Lecture by  Lars Kaderali on Mathematical Models of Infection and Immune Response

17:05 - 17:25 Talk by Svenja Kemmer on Model-based analysis of ligand- and drug-induced growth regulation in breast cancer

17:25 - 17:45 Talk by Bodo Lange on Predictive Modeling, Applied to Genetically Engineered Mouse Models of Breast or Lung Cancer, Provides Insights into Major Oncogenic Pathways

17:45 - 18:05 Talk by Charles Barker on A Modular, Hierarchical Model of Melanoma Cell Signaling

18:05 - 18:25 Talk by Annika Röhl on Fetal Lung Functional Module and COPD Module are in Close Vicinity in the Human Interactome

Dinner and get-together
Bar is reserved for the evening


Tuesday, November 26

09:00 - 09:50 Keynote Lecture by Julio Banga on Optimal control in systems medicine

09:50 - 10:10 Talk by Matthias Chung  on From Parameter and Uncertainty Estimation to Optimal Experimental Design: Challenges in Biological Dynamical Systems Inference

10:10 - 10:30 Talk by Leonard Schmiester on Efficient Parameter Estimation Methods for Integration of Qualitative Data in Quantitative Models

Coffee break & Poster Session 1

11:40 - 12:30 Keynote Lecture by  Ursula Kummer on Multi-scale modeling integrating cellular mechanistic and whole-body physiologically-based pharmacokinetic (PBPK) models


13:30 - 13:50 Talk by Wolfgang Müller on Improving Model Understanding and Reuse Through Standards and Common Knowledge Representation

13:50 - 14:40 Keynote Lecture by Matthias König on Computational modeling of liver function tests - Stratification and individualization using standardized models and data

14:40 - 15:00 Talk by Martina Kutmon on WikiPathways: Curation, Visualization and Analysis of Biological Pathway

15:00 - 15:20 Talk by Kai Budde on Reusing provenance information captured in WebProv for automatic generation of experiment specifications

Coffee break & Poster Session 2

16:50 - 17:50 Plenary discussion

Conference Dinner at Berlin Fernsehturm


Wednesday, November 27

09:00 - 09:20 Talk by Lukas Refisch on ODE-based Modelling of Binding Kinetics from Aptamer Microarrays

09:20 - 09:40 Talk by Zahra Sadat Hajseyed Nasrollah  on Learning the Topology of Latent Signaling Networks from High Dimensional Transcriptional Intervention Effect

09:40 - 10:00 Talk by Wilhelm Huisinga on Sensitivity Based Input-Response Index to Analyse and Reduce Large-Scale Signalling Networks

10:00 - 10:20 Talk by Abhishek Upadhyay on An Inactivation Switch Enables Rhythms in a Neurospora Clock Model [see talk on video]

Coffee break

10:50 - 11:40  Keynote Lecture by Jörn Starruß on Modelling and Simulation of Multi-Cellular Processes using Morpheus

11:40 - 12:00  Talk by Andrei Kramer on Software Development for Bayesian Parameter Sampling of Large Intracellular Models

12:00 - 12:20  Talk by Elba Raimundez on Efficient sampling by marginalization of scaling parameters for mechanistic models with relative data


13:30 - 14:20 Keynote Lecture by Jana Wolf on Modelling signal transduction and gene regulation at the interface of single-cell and population data

14:20 - 14:30 Closing remarks



Wednesday, November 27

Coffee break

16:00 - 16:30 Presentation of hackathon topics
16:30 - 18:00  Formation of topic groups and tutorials
                        1) Tutorial on multi-cellular modelling
               - Jörn Starruß on Modelling and Simulation of Multi-Cellular Processes using Morpheus
               - Emad Alamoudi & Yannik Schälte on Parameter estimation using pyABC
                        2) Tutorial on model merging (by Tom Gebhardt)


Thursday, November 28

 09:00 - 12:30  Hacking and tutorials (with a coffee break at around 10:00)
 12:30 - 13:30  Lunch
 13:30 - 18:00  Hacking (with a coffee break at around 15:30)
 19:00 - 20:30  Dinner at Clärchens Ballhaus

Friday, November 29

 09:00 - 12:30  Hacking (with a coffee break at around 10:00)
 12:30 - 13:30  Lunch
 13:30 - 14:30  Hacking
 14:30 - 15:00  Summary and closing remarks


Please find the proceedings for the conference here.




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