Preliminary Program



Monday, November 25

12:00               Registration opens 

13:30 - 13:50  Welcome by organizers

13:50 - 14:40 Keynote lecture by Melanie Stefan on Rule-based modelling of protein regulation in the synapse

14:40 - 15:30 Keynote Lecture by Lars Kaderali on Mathematical Models of Infection and Immune Response

Coffee break

16:00 - 16:50 Keynote Lecture by Birgit Schöberl on The Role of Quantitative Systems Pharmacology in Translational Medicine

16:50 - 17:10 Talk by Svenja Kemmer on Model-based analysis of ligand- and drug-induced growth regulation in breast cancer

17:10 - 17:30 Talk by Bodo Lange on Predictive Modeling, Applied to Genetically Engineered Mouse Models of Breast or Lung Cancer, Provides Insights into Major Oncogenic Pathways

17:30 - 17:50 Talk by Charles Barker on A Modular, Hierarchical Model of Melanoma Cell Signaling

17:50 - 18:10 Talk by Annika Röhl on Fetal Lung Functional Module and COPD Module are in Close Vicinity in the Human Interactome

Dinner and get-together
Bar is reserved for the evening


Tuesday, November 26

09:00 - 09:50 Keynote Lecture by Julio Banga on Optimal control in systems medicine

09:50 - 10:10 Talk by Matthias Chung  on From Parameter and Uncertainty Estimation to Optimal Experimental Design: Challenges in Biological Dynamical Systems Inference

10:10 - 10:30 Talk by Leonard Schmiester on Efficient Parameter Estimation Methods for Integration of Qualitative Data in Quantitative Models

Coffee break & Poster Session 1

11:40 - 12:30 Keynote Lecture by  Ursula Kummer on Multi-scale modeling integrating cellular mechanistic and whole-body physiologically-based pharmacokinetic (PBPK) models


14:00 - 14:50 Keynote Lecture by Matthias König on Computational modeling of liver function tests - Stratification and individualization using standardized models and data

14:50 - 15:10 Talk by Dagmar Waltemath on Improving Model Understanding and Reuse Through Standards and Common Knowledge Representation

15:10 - 15:30 Talk by Martina Kutmon on WikiPathways: Curation, Visualization and Analysis of Biological Pathway

15:30 - 15:50 Talk by Kai Budde on Reusing provenance information captured in WebProv for automatic generation of experiment specifications

Coffee break & Poster Session 2

17:30 - 18:30 Plenary discussion

Conference Dinner at Berlin Fernsehturm


Wednesday, November 27

09:00 - 09:50 Keynote Lecture by Ramon Grima on Analytical approximations for spatial and non-spatial stochastic biochemical kinetics

09:50 - 10:10 Talk by Wilhelm Huisinga on Sensitivity Based Input-Response Index to Analyse and Reduce Large-Scale Signalling Networks

10:11 – 10:30 Talk by Abhishek Upadhyay on An Inactivation Switch Enables Rhythms in a Neurospora Clock Model

Coffee break

11:00 - 11:20  Talk by Lukas Refisch on ODE-based Modelling of Binding Kinetics from Aptamer Microarrays

11:20 - 11:40  Talk by Zahra Sadat Hajseyed Nasrollah  on Learning the Topology of Latent Signaling Networks from High Dimensional Transcriptional Intervention Effects

11:40 - 12:00  Talk by Andrei Kramer on Software Development for Bayesian Parameter Sampling of Large Intracellular Models

12:00 - 12:20  Talk by Elba Raimundez on Efficient sampling by marginalization of scaling parameters for mechanistic models with relative data


14:00 - 14:50 Keynote Lecture by Jana Wolf on Modelling signal transduction and gene regulation at the interface of single-cell and population data

14:50 - 15:00 Closing remarks



1. One topic / project on multi-cellular modelling with short talks by

a. Jörn Starruß on Modelling and Simulation of Multi-Cellular Processes using Morpheus

               b. Emad Alamoudi & Yannik Schälte on Integrating pyABC and Morpheus for the Simulation and Parameterization of Computational Models of Multi-Cellular Processes

2. One topic/ project on model merging with short talks by

                     a. Tom Gebhardt  on Model Version Merging




Dr. Anandhi Iyappan 
Science Manager 
Institute of Computational Biology 
Helmholtz Zentrum München (GmbH) 

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